Prequel : Project … hunted !
Hmmm …
There are many subtle nuances that have to be kept in mind while you do this project.
Not at all that easy. The pre-planning is very very important. Have to proceed very carefully, for the territory is vastly unknown, though familiar. For example, we were thinking of getting the DNA samples from biopsy tissues, but just yesterday got to know in a mini-brainstorming with Navoneel da, a rersearch scholar in Human Genetics Unit at our insti that there is a phenomenon called heteroplasmy. What happens is cancerous cells have very high mutation rates, so drastic such that even the timid mitochondrial DNAs are affected. And what more, this research has been recently done in our institute itself recently. That’s why it is safe to take peripheral blood samples, not biopsy tissues, to be completely foolproof.
And this is only a part of it. There are some areas on which we are trying to think originally, but the basics turned out to be quite frail yesterday.
Have to study about it. A lot. Varied. More theoretical background needed. More efforts needed. More thinking needed.
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